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Monday Aug. 21 |
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Opening |
Institutional welcoming by Alberto and Eoin |
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19:00 |
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Carrozza, M. – Municipality of Sirmione |
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Castelli, F. – Rector of the University of Brescia |
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Wine and cheese welcoming |
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Tuesday Aug. 22 |
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Session 1 |
Nuclear Mechanobiology |
Char: M. Bacca |
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9:00 |
9:30 |
Shenoy, V., How do Forces From the Cell’s Environment Affect DNA Organization? |
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9:30 |
10:00 |
Roca-Cusachs, P., Controlling nuclear mechanics from the extracellular matrix |
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Coffee break |
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Session 2 |
Morphogenesis |
Chair: A. Gizzi |
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10:30 |
11:00 |
Garcia-Aznar, JM., Unraveling the morphogenetic pattern of cystic spheroids: an AI-guided physics-based approach |
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11:00 |
11:30 |
Deshpande, V., The role of geometry and boundary conditions in cell organisation in tissue morphogenesis |
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11:30 |
12:00 |
Rangamani, P., Multiscale modeling of lipid bilayers for mitochondrial membrane mechanics. |
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12:00 |
12:30 |
Saif, T., Disorder to order transition in multicellular systems through dynamic nonlinear elastic interactions |
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Lunch break |
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Session 3 |
Mechanobiology of vascular systems |
Chair: V. Vogel |
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14:00 |
14:30 |
Loerakker, S., Computational approaches to analyze and predict cell-mediated cardiovascular growth and remodeling |
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14:30 |
15:00 |
Conte, V., The border zone in myocardial infarction: the mechanobiological perspective of cells |
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15:00 |
15:30 |
Schön, I., Mechanobiology of platelet-extracellular matrix interactions during thrombus formation |
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15:30 |
16:00 |
Ristori, T., Multiscale modelling of the spatiotemporal dynamics of angiogenesis in regenerative medicine |
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Coffee break |
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Session 4 |
Active contractility |
Chair: V. Deshpande |
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16:30 |
17:00 |
McGarry, P., Modelling active contractility in cells and tissue |
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17:00 |
17:30 |
Nardinocchi, P., Self-contractile biopolymer gels: a continuum mechanics perspective |
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17:30 |
18:00 |
Smith, M., Tensional homeostasis: role of signaling and contractile machinery in suppression of mechanical extremes |
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Wednesday Aug. 23 |
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Session 5 |
Mechanobiology of cancer |
Chair: V. Shenoy |
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9:00 |
9:30 |
Gräter, F., Protein mechanoradicals: how tissues turn mechanical into oxidative stress |
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9:30 |
10:00 |
McNamara, L., Osteocyte mechanobiology and bone disease: multicellular models to study bone loss during estrogen deficiency and bone metastases |
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10:00 |
10:30 |
McEvoy, E., Mechanobiology of stress-dependent cell and tumour growth |
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Coffee break |
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Session 6 |
Cellular Motility |
Chair: P. McGarry |
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11:00 |
11:30 |
Doyle, A., Cell mechanics and motility in 3D microenvironments |
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11:30 |
12:00 |
Madzvamuse, A., Unravelling mechano-biochemical models for 2- and 3-D single cell migration |
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12:00 |
12:30 |
Salvadori, A., Actin-based motility unveiled: from bacteria to cells |
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Lunch break |
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Session 7a |
Fluidics and Organs on a chip |
Chair: A. Gizzi |
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14:00 |
14:30 |
Occhetta, P., BiomimX, Beating organs-on-chip as innovative tools for diseases modelling and advanced therapies evaluation |
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14:30 |
15:00 |
Vassalli, M., Fluidic Force Microscopy to study Cellular Mechanosensing |
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Session 7b |
Extracellular Matrix |
Chair: P. Roca-Cusachs |
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15:00 |
15:30 |
Genin, G., Cell-matrix feedback and the development of polarity |
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15:30 |
16:00 |
Vogel, V., Bridging Length Scales: Mechano-Chemical Switching of Extracellular Matrix Fibers |
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16:00 |
16:30 |
Gizzi, A., Growth and remodeling in distributed fiber-reinforced materials |
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16:30 |
17:00 |
Pathak, A., Environmental memory and cell invasion through fibrous microenvironments |
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18:30 |
23:00 |
Poster session and social dinner Podere Selva Capuzza, Desenzano del Garda |
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Thursday August 24 |
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Session 8 |
Experimental and Theoretical Mechanobiology, 1. |
Chair: E. McEvoy |
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9:00 |
9:30 |
Bacca, M., Energetics of Diffusion-mediated Processes in Biological Systems: Virus Replication & Cytoskeletal Contraction |
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9:30 |
10:00 |
Kaul, H., Synergy between mechanics and biochemical signalling hinges on cellular energetics |
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10:00 |
10:30 |
Klotzsch, E., Lymphocyte mechano-stimulation for adoptive immunotherapies |
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Coffee break |
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Session 9 |
Experimental and Theoretical Mechanobiology, 2 |
Chair: A. Doyle |
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11:00 |
11:30 |
Jungmann, R., Localizomics: towards spatial omics using DNA-based super-resolution microscopy |
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11:30 |
12:00 |
Alvarado, J., Connecting active “hardware” to biological “software” |
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12:00 |
12:30 |
Cheng, L., Experimental and modelling techniques for quantifying the electro-mechanical activity in the gut |
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Lunch break |
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Session 11 |
Multicellular systems |
Chair: A. Salvadori |
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14:00 |
14:30 |
Marino, M., Phase-field modeling of cell motility in biodegradable hydrogel scaffolds |
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14:30 |
15:00 |
Scita, G., Tissue fluidification in pathophysiology |
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15:00 |
15:30 |
Arroyo, M., A mechano-biological feedback between cancer organoids and the ECM initiates and sustains collective invasion |
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Closing by Alessio and Mattia |
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